Pereira GH, Pádua SS, Park MV, Muller RP, Passos RM, Menezes Y
Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia. [Journal Article]
Braz J Infect Dis 2008 Dec; 12(6):555-7.
Meningitis is a common evolution in progressive disseminated histoplasmosis in children, and is asymptomatic in many cases. In leukemia, the impaired of the T cells function can predispose to the disseminated form. The attributed mortality rate in this case is 20%-40% and the relapse rate is as high as 50%; therefore, prolonged treatment may be emphasized. We have described a child with acute myeloid leukemia (AML), that developed skin lesions and asymptomatic chronic meningitis, with a good evolution after prolonged treatment with amphotericin B deoxycholate followed by fluconazole.
More from this journal |
