| Title | The use of thalidomide in the management of bleeding from a gastric cancer. | | Author(s) | Lambert K, Ward J | | Institution | Mid Yorkshire Hospitals NHS Trust, Dewsbury and District Hospital, Dewsbury. | | Source | Palliat Med 2009 Mar 20. | | Abstract | Medical management of severe gastrointestinal bleeding can present a therapeutic challenge. We describe a case of bleeding secondary to gastric cancer that failed to settle, despite treatment with tranexamic acid, etamsylate and sucralfate. Thalidomide was prescribed for its antiangiogenic properties. Bleeding settled within 1 week of starting 300 mg of thalidomide nocte. The effect appeared to be dose dependant, with bleeding recurring only when the dose was reduced to 100 mg of thalidomide nocte. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19304809 |
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