| Title | Sarcoid-like granulomas in common variable immunodeficiency. | | Author(s) | Artac H, Bozkurt B, Talim B, Reisli I | | Institution | Department of Pediatrics, Division of Immunology and Allergy, Selcuk University Meram Medical Faculty, Konya, Turkey, hasibeartac@yahoo.com. | | Source | Rheumatol Int 2009 Mar 27. | | Abstract | Common variable immunodeficiency (CVID) is a disorder characterized by hypogammaglobulinemia, poor antibody responses and recurrent bacterial infections. CVID patients have a higher prevalence of autoimmune disease and some of them develop noncaseating granulomas of the lungs, spleen, liver, skin, lymph nodes and eye. We report herein a 5-year-old girl with CVID presented with cutaneous nodules, granulomatous uveitis and oligoarthritis. The lesions, arthritis and uveitis responded well to treatment with the systemic administration of steroid. Different autoimmune diseases could be seen together in children with CVID. These patients require therapeutic cooperation of the immunologists with different specialists, including dermatologists, rheumatologists and ophthalmologists. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19326121 |
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