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Bisphosphonates and osteonecrosis: potential treatment or serious complication? The Orthopedic clinics of North America [Orthop Clin North Am] Journal article

 
Goytia RN, Salama A, Khanuja HS 
Bisphosphonates and osteonecrosis: potential treatment or serious complication? [Journal Article, Review]
Orthop Clin North Am 2009 Apr; 40(2):223-34.


They are commonly used to treat osteoporosis and other diseases that involve osteoclast-mediated bone resorption, including Paget's disease and multiple myeloma. Their use in treating osteonecrosis of the femoral head has been studied and theoretically holds promise. There are complications associated with these medications, however, including the development of osteonecrosis in the jaw.



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