| Title | Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging. | | Author(s) | Lee JH, Dyke JP, Ballon D, Ciombor DM, Tung G, Aaron RK | | Institution | Department of Orthopaedic Surgery, Columbia University Medical Center, 622 West 168th Street, PH 1130, New York, NY 10032, USA. | | Source | Orthop Clin North Am 2009 Apr; 40(2):249-57. | | MeSH | Adult
Aged
Aged, 80 and over
Animals
Bone Marrow Diseases
Contrast Media
Diagnosis, Differential
Disease Models, Animal
Edema
Femur Head
Follow-Up Studies
Gadolinium DTPA
Guinea Pigs
Humans
Injections, Intravenous
Knee Joint
Magnetic Resonance Imaging
Middle Aged
Osteoarthritis, Hip
Osteoarthritis, Knee
Osteonecrosis
Syndrome
Young Adult
| | Abstract | Osteoarthritis and avascular necrosis are common clinical entities with unknown origins. Recently, vascular changes were implicated in the pathogenesis of both conditions. This article discusses the use of novel noninvasive imaging techniques as a means of assessing bone perfusion and quantifying differences seen in osteoarthritis and avascular necrosis. Review of our human data suggests that the MRI contrast dye is retained for longer periods of time, suggesting decreased perfusion out of regions of osteoarthritis and avascular necrosis. Use of such a noninvasive measure of assessing bone perfusion could be useful in the diagnosis, prevention, and treatment of not only osteoarthritis and avascular necrosis but also other entities that affect the musculoskeletal system. | | Language | eng | | Pub Type(s) | Comparative Study
Journal Article
| | PubMed ID | 19358910 |
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