Extended treatment of older cigarette smokers. Addiction (Abingdon, England) [Addiction] Journal article | | Title | Extended treatment of older cigarette smokers. | | Author(s) | Hall SM, Humfleet GL, Muñoz RF, Reus VI, Robbins JA, Prochaska JJ | | Institution | University of California, San Francisco, CA 94143-0984, USA. shall@lppi.ucsf.edu | | Source | Addiction 2009 Jun; 104(6):1043-52. | | MeSH | Aged
Aged, 80 and over
Bupropion
Cognitive Therapy
Dopamine Uptake Inhibitors
Female
Humans
Male
Middle Aged
Nicotine
Program Evaluation
Smoking Cessation
Time Factors
Tobacco Use Disorder
Treatment Outcome
| | Abstract | AIMS: Tobacco dependence treatments achieve abstinence rates of 25-30% at 1 year. Low rates may reflect failure to conceptualize tobacco dependence as a chronic disorder. The aims of the present study were to determine the efficacy of extended cognitive behavioral and pharmacological interventions in smokers > or = 50 years of age, and to determine if gender differences in efficacy existed.
DESIGN: Open randomized clinical trial.
SETTING: A free-standing, smoking treatment research clinic.
PARTICIPANTS: A total of 402 smokers of > or = 10 cigarettes per day, all 50 years of age or older.
INTERVENTION: Participants completed a 12-week treatment that included group counseling, nicotine replacement therapy (NRT) and bupropion. Participants, independent of smoking status, were then assigned randomly to follow-up conditions: (i) standard treatment (ST; no further treatment); (ii) extended NRT (E-NRT; 40 weeks of nicotine gum availability); (iii) extended cognitive behavioral therapy (E-CBT; 11 cognitive behavioral sessions over a 40-week period); or (iv) E-CBT plus E-NRT (E-combined; 11 cognitive behavioral sessions plus 40 weeks nicotine gum availability).
MEASUREMENTS: Primary outcome variable was 7-day point prevalence cigarette abstinence verified biochemically at weeks 24, 52, 64 and 104.
FINDINGS: The most clinically important findings were significant main effects for treatment condition, time and the treatment x time interaction. The E-CBT condition produced high cigarette abstinence rates that were maintained throughout the 2-year study period [(week 24 (58%), 52 (55%), 64 (55%) and 104 (55%)], and was significantly more effective than E-NRT and ST across that period. No other treatment condition was significantly different to ST. No effects for gender were found.
CONCLUSIONS: Extended cognitive behavioral treatments can produce high and stable cigarette abstinence rates for both men and women. NRT does not add to the efficacy of extended CBT, and may hamper its efficacy. Research is needed to determine if these results can be replicated in a sample with a greater range of ages, and improved upon with the addition of medications other than NRT. | | Language | eng | | Pub Type(s) | Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
| | PubMed ID | 19392908 |
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