Arpesella R, Dallocchio C, Arbasino C, Imberti R, Martinotti R, Frucht SJ A patient with intractable posthypoxic myoclonus (Lance-Adams syndrome) treated with sodium oxybate. [Journal Article] Anaesth Intensive Care 2009 Mar; 37(2):314-8.
Posthypoxic myoclonus is a rare and devastating complication of near-fatal cardiopulmonary arrest. Despite treatment with available anti-myoclonic agents, some patients may recover cognitively but remain completely disabled by severe myoclonus. We report a 16-year-old patient with severe treatment-refractory posthypoxic myoclonus, which improved markedly with administration of the drug sodium oxybate.
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