| Title | Myocardial infarction associated with the administration of intravenous ephedrine and metaraminol for spinal-induced hypotension. |
| Author(s) | Khavandi A, Gatward JJ, Whitaker J, Walker P |
| Institution | Department of Cardiology, Southmead Hospital, North Bristol NHS Trust, Southmead Road, Bristol BS10 5NB, UK. |
| Source | Anaesthesia 2009 May; 64(5):563-6. |
| MeSH | Adult
Anesthesia, Spinal
Drug Therapy, Combination
Ephedrine
Female
Humans
Hypotension
Intraoperative Complications
Metaraminol
Myocardial Infarction
Vasoconstrictor Agents
|
| Abstract | A 31-year-old female with no risk factors for cardiac disease suffered a peri-operative myocardial infarction during an elective gynaecological procedure under spinal anaesthesia. The timing and nature of cardiac symptoms suggest that the myocardial infarction was caused by coronary artery vasospasm secondary to ephedrine and/or metaraminol, which were administered to treat spinal-induced hypotension. We review the recent literature and case reports on myocardial infarction attributed to sympathomimetic drugs, and recommend the use of sublingual or intravenous nitrates when signs or symptoms of coronary arterial vasospasm become evident during their use. |
| Language | eng |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 19413828 |
