| Title | Hypoglycaemic and hypolipidaemic effect of aqueous leaf extract of Murraya koenighii in normal and alloxan-diabetic rats. | | Author(s) | Lawal HA, Atiku MK, Khelpai DG, Wannang NN | | Institution | Department of Biochemistry, Bayero University, P. M. B. 3011, Kano,Nigeria. | | Source | Niger J Physiol Sci 2008 Jun-Dec; 23(1-2):37-40. | | Abstract | The hypoglycaemic effect of aqueous leaf extract of Murraya koenigii was studied in normal and alloxan0-nduced diabetic rats. The extract was administered orally at 100 mg/Kg, 150 mg/Kg and 200 mg/Kg bodyweight each to respective groups of animals (Groups I, II and III) for seven days. Group IV received normal saline and served as control for the normal rats. For the alloxan-induced diabetic rats, the same dosage pattern was administered to three groups of rats for seven days (Groups V, VI and VII) while group VIII which received normal saline served as control. At the various dose levels administered, the glucose lowering effect was more pronounced in the alloxan-diabetic rats than in control rats. When compared with chlorpropamide, the glucose lowering effect of aqueous extract of Murraya koenigii was significantly [P < 0.05] lower at the dose levels administered in both normal and alloxan-diabetic rats. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19434212 |
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