Wang H, Wang Y, Shi Y, Li X, Long C
Chemical constituents in roots of Osbeckia opipara. [Journal Article, Research Support, Non-U.S. Gov't]
Zhongguo Zhong Yao Za Zhi 2009 Feb; 34(4):414-8.
OBJECTIVE: To study the chemical constituents of the roots of Osbeckia opipara.
METHOD: Repeated column chromatography over silica gel, RP-18 and Sephadex LH-20, and preparative thin layer chromatography(PTLC) were used to isolate the compounds, whose structures were determined by spectroscopic methods by direct comparing spectral data with those reported references.
RESULT: From the MeOH extract of the roots O. opipara, twelve compounds were isolated and identified as follows: lasiodiplodin (1) , de-O-methyllasiodiplodin (2), 2, 3- dihydro-2-hydroxy-2, 4-dimethyl-5-trans-propenylfuran-3-one (3), integracin (4), 5alpha, 8alpha-epidioxy-(22E, 24R)-ergosta-6, 22-dien-3beta-ol (5), 3, 3', 4'-tri-O-methylellagic acid (6), 5-hydroxymethyl furaldehyde (7), vomifolio (8) , betulintic acid (9), 2alpha-hydroxyursolic acid (10), (24R)-stigmast-4-ene-3-one (11), and eugenitin (12).
CONCLUSION: Compounds 1-12 were isolated from O. opipara for the first time.
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