| Title | Accidental acute clidinium toxicity. | | Author(s) | Richardson SE, Edwards K | | Institution | Dr S E Richardson, Emergency Department, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK; serichardson@doctors.org.uk. | | Source | Emerg Med J 2009 Jun; 26(6):460. | | Abstract | Clidinium bromide (N-methyl-quinuclidinyl-benzylate) is a rarely used antimuscarinic drug that is marketed in combination with chlordiazepoxide as an antispasmodic for use in irritable bowel syndrome. A case is reported of an accidental staggered overdose of clidinium bromide 50 mg in a patient using illicit chlordiazepoxide. The presenting features were mildly dilated pupils and palpitation secondary to sinus tachycardia that persisted for 11 h after the time of first ingestion. Emergency physicians should be aware of the potential for antimuscarinic toxicity in patients using illicit chlordiazepoxide. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19465630 |
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