Borovskaya TG, Perova AV, Pachomova AV, Poluektova ME, Gol'dberg VE
The stage of offspring of female rats after treatment with cytostatics of various groups. [Journal Article]
Bull Exp Biol Med 2008 Oct; 146(4):429-32.
We examined the offspring of female rats that were mated with intact males in the delayed period after administration of cytostatic drugs Farmorubicin, platidiam, carboplatin, etoposide, and paclitaxel (1, 3, and 6 months post-treatment). Toxicity of these drugs in the offspring decreased in the following order: paclitaxel > etoposide > carboplatin > platidiam > Farmorubicin. The toxic effect depended not only on the type of cytostatic treatment, but also on the period of conception.
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