| Title | Quantitative (35)Cl Nuclear Quadrupole Resonance in Tablets of the Antidiabetic Medicine Diabinese. | | Author(s) | Tate E, Althoefer K, Barras J, Rowe MD, Smith JA, Pearce GE, Wren SA | | Institution | King's College London, Department of Mechanical Engineering, Strand, London, WC2R 2LS, United Kingdom. | | Source | Anal Chem 2009 Jun 3. | | Abstract | Pulsed (35)Cl nuclear quadrupole resonance (NQR) experiments have been performed on 250-mg tablets of the antidiabetic medicine Diabinese to establish the conditions needed for noninvasive quantitative analysis of the medicine in standard bottles. One important condition is the generation of a uniform radio-frequency (RF) field over the sample, which has been achieved by two designs of sample coil: one of variable pitch, and the other a resonator that has been fabricated from a single turn of copper sheet with a longitudinal gap bridged by tuning capacitors. The results from blind tests show that the number of tablets in a bottle could be predicted to within +/-3%. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19492808 |
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