| Title | Relative efficacies: antimalarials to abatacept - the choice is ours. | | Author(s) | Russell AS | | Institution | University of Alberta, 562 Heritage Medical Research Centre, Edmonton, Alberta T6G 2S2, Canada. asr@gpu.srv.ualberta.ca | | Source | J Rheumatol Suppl 2009 Jun.:17-24. | | MeSH | Antibodies, Monoclonal
Antimalarials
Antirheumatic Agents
Arthritis, Rheumatoid
Disease Progression
Drug Therapy, Combination
Early Diagnosis
Humans
Immunoconjugates
Medication Adherence
Patient Selection
Time Factors
Treatment Outcome
Tumor Necrosis Factor-alpha
| | Abstract | Early diagnosis and treatment of rheumatoid arthritis (RA) are important in order to halt disease progression and joint destruction, and minimize loss of function. Individually, the disease modifying antirheumatic drugs have demonstrated similar efficacies in radiological and clinical outcomes. However, various combination therapies have been shown to improve therapeutic outcomes for patients who fail to respond adequately to monotherapy. With the introduction of the cytokine inhibitors and the development of newer biologic therapies, a number of treatment options are available for patients with RA. The efficacies of the various treatment strategies are reviewed. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
Review
| | PubMed ID | 19509326 |
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