| Title | Effects of plant water-soluble polysaccharides on the production of immunoglobulins e and g1 by lymphocytes of mice sensitized with ovalbumin. | | Author(s) | Danilets MG, Belska NV, Bel'sky YP, Uchasova EG, Trophimova ES, Ligatcheva AA, Guriev AM, Belousov MV, Ahmedganov RR, Usubov MS, Agaphonov VI | | Institution | Institute of Pharmacology, Siberian Division of Russian Academy of Medical Sciences; Siberian State Medical University, Russian Ministry of Health, Tomsk, Russia. natalybelska@yandex.ru. | | Source | Bull Exp Biol Med 2008 Nov; 146(5):585-7. | | Abstract | Were studied the effects of water-soluble plant polysaccharides isolated from pharmacopoeic raw material on anaphylactic shock and production of IgE and IgG1 by lymphocytes from mice immunized with ovalbumin. Course treatment with polysaccharides from coltsfoot, sweet flag, clover, Artemisia, marigold, and elecampane reduced animal mortality after induction of anaphylactic shock. In addition, injection of these substances reduced serum concentrations of IgE and IgG1. These substances can be regarded as promising agents for the treatment of IgE-dependent diseases (atopic dermatitis, asthma, atopic rhinitis, urticaria, food allergies, etc.). | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19526097 |
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