| Title | Antiarrhythmic activity of phytoadaptogens in short-term ischemia-reperfusion of the heart and postinfarction cardiosclerosis. | | Author(s) | Maslov LN, Lishmanov YB, Arbuzov AG, Krylatov AV, Budankova EV, Konkovskaya YN, Burkova VN, Severova EA | | Institution | Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia. maslov@cardio.tsu.ru | | Source | Bull Exp Biol Med 2009 Mar; 147(3):331-4. | | MeSH | Animals
Anti-Arrhythmia Agents
Aralia
Arrhythmias, Cardiac
Eleutherococcus
Leuzea
Myocardial Reperfusion Injury
Panax
Plant Extracts
Rats
Rats, Wistar
Rhodiola
Ventricular Fibrillation
| | Abstract | A course of treatment (16 mg/kg orally during 5 days) by Aralia mandshurica or Rhodiola rosea extracts reduced the incidence of ischemic and reperfusion ventricular arrhythmias during 10-min ischemia and 10-min reperfusion. Extracts of Eleutherococcus senticosus, Leuzea carthamoides, and Panax ginseng did not change the incidence of ischemic and reperfusion arrhythmias. Chronic treatment by aralia, rhodiola, and eleutherococcus elevated the ventricular fibrillation threshold in rats with postinfarction cardiosclerosis. Ginseng and leuzea did not change this parameter in rats with postinfarction cardiosclerosis. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19529855 |
|
