Rozin AP, Kagna O, Shiller Y
Sacroiliitis and severe disability due to isotretinoin therapy. [JOURNAL ARTICLE]
Rheumatol Int 2009 Jun 17.
We report a case of acute sacroiliitis with severe disability after only 3 weeks of isotretinoin therapy with graduate reduction of pain, limitation and muscle incompetence after discontinuation of the drug and ACTH-depo injection and Ethodolac therapy. Naranjo probability scale indicated a probable relationship between isotretinoin therapy and bilateral sacroiliitis. We discussed possible mechanisms of sacroiliitis and disability due to isotretinoin treatment.
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