Alvarez A, Moncayo JI, Santacruz JJ, Santacoloma M, Corredor LF, Reinosa E
Antimicrobial susceptibility and mutations involved in clarithromycin resistance in Helicobacter pylori, isolated from patients in the Colombian western central region. [JOURNAL ARTICLE]
Antimicrob Agents Chemother 2009 Jun 22.
In a total of 106 H. pylori isolates, resistance to metronidazole, clarithromycin and amoxicillin was found in 82%, 3.8% and 1.9% of the isolates, respectively. No tetracycline-resistant isolates were found. In all clarithromycin-resistant isolates, only one point mutation was present, either A2143G or A2142G. Our results indicate that metronidazole should not be included in the empirical treatment of H. pylori infection in this region.
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