Identification of Mosaic Neisseria gonorrhoeae Penicillin-Binding Protein 2 -- 2008, San Francisco, California. Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] Journal article | | Title | Identification of Mosaic Neisseria gonorrhoeae Penicillin-Binding Protein 2 -- 2008, San Francisco, California. | | Author(s) | Pandori M, Barry PM, Wu A, Ren A, Whittington WL, Liska S, Klausner JD | | Institution | San Francisco Department of Public Health; University of California, San Francisco; University of Washington. | | Source | Antimicrob Agents Chemother 2009 Jun 22. | | Abstract | Using a real-time PCR assay specific for a mosaic penA allele that has been associated with oral cephalosporin resistance in Asia, fifty-four available Neisseria gonorrhoeae isolates collected in San Francisco from January-October, 2008 were analyzed. Five isolates tested positive for the mosaic penA gene by real-time PCR. DNA Sequencing revealed two mosaic penA alleles (SF-A and SF-B). Isolates with SF-A and SF-B alleles possessed elevated MIC for the oral cephalosporins cefpodoxime and cefixime. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19546370 |
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