| Title | Interval of Injections of Intramuscular Depot Medroxyprogesterone Acetate in the Long-Term Treatment of Endometriosis-Associated Pain: A Randomized Comparative Trial. | | Author(s) | Cheewadhanaraks S, Peeyananjarassri K, Choksuchat C, Dhanaworavibul K, Choobun T, Bunyapipat S | | Institution | Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand. | | Source | Gynecol Obstet Invest 2009 Jun 24; 68(2):116-121. | | Abstract | Aim: To determine the optimal interval of injections of intramuscular depot medroxyprogesterone acetate 150 mg in the long-term treatment of endometriosis-associated pain. Method: 112 patients with symptomatic endometriosis were randomized to receive either injections every month for 6 months, then every 3 months for a total of 15 months or injections every 3 months for 15 months. The primary outcome measure was patients' satisfaction. Result: At months 3, 6, 9, 12 and 15 of the treatment phase, there was no statistically significant difference of percentages of patients with satisfaction between the two regimens (85.7 vs. 76.8%, 76.8 vs. 73.2%, 66.1 vs. 58.9%, 60.7 vs. 55.4%, 60.7 vs. 55.4%, respectively).
Conclusion: The optimal interval of injections of depot medroxyprogesterone acetate 150 mg is every 3 months. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19556801 |
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