| Title | In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal. | | Author(s) | Jiang Z, Holyoak GR, Bartels KE, Ritchey JW, Xu G, Bunting CF, Slobodov G, Piao D | | Institution | Oklahoma State University, School of Electrical and Computer Engineering, Stillwater, Oklahoma 74078Oklahoma State University, Department of Veterinary Clinical Sciences, Stillwater, Oklahoma 74078Oklahoma State University, Department of Veterinary Pathobiology, Stillwater, Oklahoma 74078University of Oklahoma Health Sciences Center, Department of Urology, Oklahoma City, Oklahoma 73104. | | Source | J Biomed Opt 2009 May/June; 14(3):030506. | | Abstract | In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as a model in the canine pelvic canal. Studies were taken longitudinally at prior to, 14 days after, and 35 days after the TVT injection. As the tumor grew, the nodules became increasingly hyperabsorptive and moderately hyperscattering on NIR. The regions of strong NIR contrast, especially on absorption images, correlated well with those of US hypoechoic masses indicative of tumors. Combining the information of trans-rectal NIR and US detected the tumor more accurately than did the US alone at 14 days postinjection. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19566288 |
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