Brochu M, Malita MF, Messier V, Doucet E, Strychar I, Lavoie JM, Prud'homme D, Rabasa-Lhoret R Resistance training does not contribute to improve the metabolic profile after a 6-month weight loss program in overweight and obese postmenopausal women. [JOURNAL ARTICLE] J Clin Endocrinol Metab 2009 Jun 30.
Context: Limited data are available regarding the impact of caloric restriction (CR) in combination with resistance training (RT) on the metabolic profile of postmenopausal women. Objective: To determine whether RT adds to CR in improving body composition and the metabolic profile. Design and Setting: Six-month randomized clinical trial. Patients: 107 postmenopausal women (BMI > 27 kg/m(2)). Intervention: 6-month caloric restriction alone or in combination with a resistance training program. Main outcome measures: Fat mass (FM), lean body mass (LBM), abdominal subcutaneous fat (ScF) and visceral fat (VF), fasting lipids, insulin sensitivity, resting blood pressure and inflammation markers. Results: Both groups were similar at baseline and significantly decreased body weight, BMI, FM, %FM, abdominal ScF and VF after the study (P < 0.001), with greater losses of %FM and trunk FM in the CR + RT group (P < 0.05). LBM significantly decreased in the CR (-0.9 +/- 2.4 kg) and the CR+RT (-0.4 +/- 2.2 kg) groups P < 0.005), with no difference between them. Both groups significantly improved plasma triglycerides, fasting insulin level, glucose disposal and markers of the inflammation profile after weight loss (P < 0.05); with no difference between groups. No improvements were observed for the other variables of interest in both groups. Conclusions: CR+RT was associated with greater losses in %FM and trunk FM compared to a CR alone. However, CR+RT was not associated with additional improvements in the metabolic profile compared to CR alone.
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