McIntyre SH, Newburn-Cook CV, O'Brien B, Demianczuk NN Effect of Older Maternal Age on the Risk of Spontaneous Preterm Labor: A Population-Based Study. [JOURNAL ARTICLE] Health Care Women Int 2009 Aug; 30(8):670-689.
To determine if older maternal age (35 years and older) at first birth was an independent risk factor for spontaneous preterm labor, we conducted a retrospective population-based cohort study. Using provincial perinatal data, we developed separate risk models for low- and high-risk women using multivariate logistic regression. We found that older maternal age exerted a direct and independent effect on spontaneous preterm labor for both nulliparous women with no preexisting chronic illnesses or pregnancy complications (low-risk) and nulliparous women who did not have any preexisting chronic illnesses, but developed one or more pregnancy complications (high-risk).
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