Unbound MEDLINE

Torticollis under Cyclobenzaprine. Pharmacology [Pharmacology] Journal article

 
TitleTorticollis under Cyclobenzaprine.
Author(s)Reuss R, Reuter I, Jauss M, Fischer F, Müller SC, Stolz E 
InstitutionDepartment of Neurology, Justus Liebig University Giessen, Giessen, Germany.
SourcePharmacology 2009 Jul 8; 84(2):91-92.
AbstractThe muscle-relaxing 5-HT(2) receptor antagonist cyclobenzaprine is structurally closely related to amitriptyline. It is widely used to treat patients presenting with back pain and fibromyalgia. Very rarely cyclobenzaprine toxicity can result in extrapyramidal symptoms, but occurrence of torticollis has not been reported so far. We report on a patient presenting with torticollis and myoclonic movements after treatment with cyclobenzaprine, who was successfully treated with intravenous biperiden. This case might be additional evidence for the necessity of appropriate dosage in case of liver impairment. Secondly there are possibly consequences as regards the therapy of motor side effects.
LanguageENG
Pub Type(s)JOURNAL ARTICLE
PubMed ID19590258
  
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