| Title | Peripheral and central levels in nasal trigeminal sensitization and desensitization. | | Author(s) | Brand G, Jacquot L | | Institution | Laboratoire de Neurosciences, Université de Franche-Comté, Place Leclerc 25000, Besançon, France. gerard.brand@univ-fcomte.fr | | Source | Rhinology 2009 Jun; 47(2):148-52. | | Abstract | In order to investigate the role of central and peripheral mechanisms in nasal trigeminal sensitization/desensitization processes, the present work recorded psychophysical (intensity ratings) and psychophysiological (skin conductance) responses to allyl isothiocyanate volatile nasal stimulation--during normal breathing--in monorhinal condition after a controlateral stimulation of the other nostril. Insofar as both nostrils are anatomically separated, modifications in responses can be interpreted as a central regulation process. Results showed that sensitization was clearly related to central mechanisms contrarily to desensitization which depended only of peripheral level. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19593971 |
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