| Title | Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome. | | Author(s) | Hokama Y, Campora CE, Hara C, Kuribayashi T, Le Huynh D, Yabusaki K | | Institution | Department of Pathology, John A. Burns School of Medicine, University of Hawaii at Mânoa, Honolulu, Hawaii 96822, USA. | | Source | J Clin Lab Anal 2009; 23(4):210-2. | | MeSH | Adult
Aged
Antibodies, Anticardiolipin
Cardiolipins
Enzyme-Linked Immunosorbent Assay
Fatigue Syndrome, Chronic
Female
Humans
Immunoglobulin Isotypes
Immunoglobulin M
Male
Middle Aged
Mitochondria, Liver
| | Abstract | Examination of anticardiolipin antibodies (ACAs) in the sera of patients clinically diagnosed with chronic fatigue syndrome (CFS) using an enzyme-linked immunoassay procedure demonstrated the presence of immunoglobulin M isotypes in 95% of CFS serum samples tested. The presence of immunoglobulin G and immunoglobulin A isotypes were also detected in a subset of the samples. Future studies will focus on elucidating whether alterations to mitochondrial inner membranes and/or metabolic functions play a possible role in the expression of ACAs. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
| | PubMed ID | 19623655 |
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