The characteristics of keratomycosis by Beauveria bassiana and its successful treatment with antimycotic agents. Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] Journal article | | Title | The characteristics of keratomycosis by Beauveria bassiana and its successful treatment with antimycotic agents. | | Author(s) | Sonoyama H, Araki-Sasaki K, Kazama S, Kawasaki T, Ideta H, Sunada A, Asari S, Inoue Y, Hayashi K | | Institution | Ideta Eye Hospital, Kumamoto, Kumamoto, Japan. | | Source | Clin Ophthalmol 2008 Sep; 2(3):675-8. | | Abstract | Clinical findings and treatment of keratomycosis caused by Beauveria bassiana, an entomopathogenic filamentous fungus, are described for an 80-year-old woman, who was referred to the hospital for ocular pain and redness on the 9th day after an ocular injury caused by the frame of her glasses. She had a long history of recurrent diabetic iritis and continuously used topical antibiotics and corticosteroids. At her first visit, a slit-lamp examination indicated a corneal ulcer confined within the superficial stromal layer, along with a slight infiltration and edema. Only a very few inflammatory cells were seen in the anterior chamber. Direct microscopic examination of corneal scrapings revealed septate fungal hyphae with zig-zag rachis and budding that was subsequently identified as B. bassiana by slide culture. Topical voriconazole with miconazole, pimaricin and oral itraconazole were effective and the lesion disappeared leaving only a mild scar at 2 months. The sensitivity of B. bassiana to various antimycotic agents was confirmed by broth microdilution, agar dilution with the Clinical Laboratory Standard Institute standard, and a disk method using topically applied concentrations. B. bassiana, which exhibits a characteristic appearance in smears and causes superficial keratomycosis, is sensitive to voriconazole with miconazole, pimaricin, and itraconazole. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19668774 |
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