| Title | Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure. | | Author(s) | Kovac S, Möddel G, Reinholz J, Alexopoulos AV, Syed T, Schuele SU, Lineweaver T, Loddenkemper T | | Institution | Neurological Institute, Cleveland Clinic, Cleveland, OH, USA; Department of Neurology, University of Muenster, Muenster, Germany. | | Source | Epilepsy Behav 2009 Aug 12. | | Abstract | OBJECTIVE: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure.
METHODS: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other.
RESULTS: Language lateralization and memory lateralization were positively correlated (r=0.34, P<0.01). Correlations differed depending on the presence and type of lesion (chi(2)=7.98, P<0.05). LIs correlated significantly higher (z=2.82, P<0.05) in patients with cortical dysplasia (n=41, r=0.61, P<0.01) compared with the group without lesions (n=90, r=0.16, P>0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P<0.01) and language (P<0.01) LIs were higher in right- compared with left-sided lesions.
CONCLUSION: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19682954 |
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