| Title | Simultaneous determination of five benzimidazoles in feeds using high-performance capillary electrophoresis. | | Author(s) | Shen J, Tong J, Jiang H, Rao Q, Li N, Guo L, Ding S | | Institution | China Agricultural University, National Reference Laboratories for Veterinary Drug Residue, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Beijing 100193, People's Republic of China. | | Source | J AOAC Int 2009 Jul-Aug; 92(4):1009-15. | | Abstract | A high-performance capillary electrophoretic method for determination of five benzimidazoles (thiabendazole, albendazole, fenbendazole, mebendazole, oxfendazole) in animal feeds was developed. Separation was carried out in an 80.5 cm x 75 microm id fused-silica uncoated capillary and injected by hydrodynamic injection (35 mbar x 8 s) at a wavelength detection of 295 nm. The drugs were completely resolved in 50 mmol/L citric acid buffer (pH 1.9) with 30 kV at a temperature of 25 degrees C. Linear range was 1-80 microg/mL; limits of detection for the analytes were less than 2 mg/kg; the overall recoveries for benzimidazoles were >73%, with coefficients of variation below 10%. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
| | PubMed ID | 19714965 |
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