| Title | Delayed graft function is reduced with antithymocyte globulin induction in pediatric kidney transplantation. | | Author(s) | Vilalta R, Lara E, Madrid A, Chocron S, Vazquez A, Casquero A, Nieto J | | Institution | Pediatric Nephrology Department, Hospital Vall d'Hebron, Barcelona, Spain. | | Source | Transplant Proc 2009 Jul-Aug; 41(6):2373-5. | | Abstract | Reduction of delayed graft function (DGF) is critical to the success of renal transplantation. We report graft outcomes with antithymocyte globulin (ATG) induction compared with using interleukin-2 receptor antagonist basiliximab (IL-2RA). Twelve pediatric patients received a pediatric deceased donor kidney. We treated them with ATG (group A, ATG; n = 6) or IL-2RA (group B, n = 6). DGF was observed in 0 cases (group A) and in 6 cases (group B), which showed a mean of 7 +/- 3 days (P < .001). In group A, lymphopenia occurred routinely resolving after 3-6 months, none with serious infection. The incidence of oportunistic infections was 0% in both groups. One-year patient and graft survivals were 100% in both groups. ATG induction significantly reduced the incidence of delayed graft function. Both induction treatments led to a good patient and graft survival. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19715923 |
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