| Title | Secondary revascularisation following intracoronary brachytherapy. | | Author(s) | Sabaté M | | Institution | Interventional Cardiology Unit, Cardiology Department, Sant Pau University Hospital, Barcelona, Spain. msabatet@santpau.cat | | Source | EuroIntervention 2009 May.:D121-6. | | Abstract | Intracoronary brachytherapy (ICB) was developed as an attempt to prevent restenosis after percutaneous coronary interventions. Early clinical experiences showed impressive results especially in the subset of patients with in-stent restenosis. This led to the design of large multicentre trials that demonstrated the efficacy of ICB as adjunctive therapy in patients with in-stent restenosis as compared to conventional treatment. Despite these outstanding initial results, several limitations arose such as late thrombosis, edge effect or late catch-up phenomenon. These, together with the difficult logistic process to implement the ICB in the cath lab and the development of the drug-eluting stent shelved definitely the technique. This review describes the potentials and limitations of this therapy, as well as the current status in the drug-eluting stent era. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19736060 |
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