| Title | Preventing viral-induced type 1 diabetes. | | Author(s) | Richer MJ, Horwitz MS | | Institution | Department of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia, Canada. | | Source | Ann N Y Acad Sci 2009 Sep.:487-92. | | Abstract | The development of type 1 diabetes is, in part, dictated by the failure of regulatory T cells to maintain peripheral tolerance. As such, therapies aimed at correcting the declining function of regulatory T cells have been the subject of intense investigation. In this review, we discuss the potential of regulatory T cells to suppress autoreactive responses and prevent type 1 diabetes induced by viral infection while maintaining protective antiviral immunity. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
| | PubMed ID | 19758190 |
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