Development of Herpes Simplex Virus Stomatitis during Receipt of Cidofovir Therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] Journal article

We report 3 children who, after undergoing hematopoietic stem cell transplant, developed herpes simplex virus (HSV) stomatitis while receiving weekly cidofovir as preemptive treatment for cytomegalovirus infection. All patients responded well to treatment with either acyclovir or ganciclovir. Despite the in vitro susceptibility of HSV to cidofovir, once-weekly treatment with this agent may not be adequate prophylaxis in pediatric patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis]