Vohra S, Akoury H, Bernstein P, Einarson TR, Pairaudeau N, Taddio A, Koren G The Effectiveness of Proctofoam-HC for Treatment of Hemorrhoids in Late Pregnancy. [Journal Article] J Obstet Gynaecol Can 2009 Jul; 31(7):654-9.
Objective: Currently no topical anti-hemorrhoidal agents have been studied for effectiveness in pregnancy. This study evaluated the effectiveness of Proctofoam-HC used during the last trimester of pregnancy. Methods: In this prospective, open-label, observational study, pregnant women prescribed Proctofoam-HC were asked to complete two telephone interview questionnaires. Results: A total of 88 women completed the study. All hemorrhoidal symptoms, including pain, pruritus, swelling, itching, decreased significantly (P < 0.001) and overall well-being improved. The improvement was clinically very significant after correction for potential placebo effect. Conclusions: Proctofoam-HC appears to provide effective treatment of hemorrhoids in late pregnancy.
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