Treatment of Chronic Idiopathic Urticaria with Levamisole: a Multicentre, Randomized, Double-blind, Controlled Trial. The Journal of international medical research [J Int Med Res] Journal article | | Title | Treatment of Chronic Idiopathic Urticaria with Levamisole: a Multicentre, Randomized, Double-blind, Controlled Trial. | | Author(s) | Zhang H, Shan C, Hua Z, Zhao P, Zhang H | | Institution | Affiliated Yancheng Hospital, Medical College of Southeast University, Yancheng, China. | | Source | J Int Med Res 2009 Jul-Aug; 37(4):1167-72. | | Abstract | The objective of this study was to evaluate the efficacy of treating chronic idiopathic urticaria (CIU) with levamisole in combination with levocetirizine. This was a multicentre, randomized, double-blind, controlled trial that included 132 patients with active CIU who were treated for 6 weeks with either levocetirizine alone (control group; n = 65) or levamisole plus levocetirizine (treatment group; n = 67). Response to therapy was evaluated by measuring the efficacy rate. After 2 weeks of treatment, there was no significant difference in the efficacy rate between the treatment and control groups (54.84% and 42.37%, respectively). After 6 weeks of treatment, a statistically significant difference in the efficacy rate was observed between the groups (76.27% and 54.39% for the treatment and control groups, respectively). This study demonstrated that a combination of levamisole plus levocetirizine is more effective than levocetirizine alone and potentially provides a new, promising approach to the treatment of CIU. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19761700 |
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