Gao J, Zhang HJ, Wu SG, Yu SH, Yoon I, Moore D, Gao YP, Yan HJ, Qi GH
Effect of Saccharomyces cerevisiae fermentation product on immune functions of broilers challenged with Eimeria tenella. [Journal Article]
Poult Sci 2009 Oct; 88(10):2141-51.
Three hundred sixty 1-d-old male Arbor Acres broilers were randomly allotted to 6 groups with a 2 x 3 factorial arrangement of treatments. Three supplemental levels (0, 0.25, and 0.50%) of Saccharomyces cerevisiae fermentation product (XP) were fed to control and Eimeria tenella-infected broilers. Growth performance and immune response criteria were measured after coccidian infection. Broiler ADG was lowered (P < 0.01) by coccidian infection and improved by XP supplementation (P = 0.04). Supplementation of XP increased CD3+, CD4+, and CD8+ T-lymphocyte counts (P < 0.05) and the ratio CD4+:CD8+ in blood (P = 0.06) and spleen (P = 0.04) as well as ileum intraepithelial lymphocyte count, cecal tonsil secretory IgA counts, serum lysozyme content (P < 0.01), and albumin:globulin ratio (P = 0.02). These results suggest that dietary XP supplementation could improve immune function and growth performance in coccidia-infected broilers.
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