| Title | An unusual case of Aspergillus fibrosing mediastinitis. | | Author(s) | Wightman SC, Kim AW, Proia LA, Faber LP, Gattuso P, Warren WH, Liptay MJ | | Institution | Division of Thoracic Surgery, Rush University Medical Center, Chicago, Illinois 60612, USA. | | Source | Ann Thorac Surg 2009 Oct; 88(4):1352-4. | | MeSH | Aged
Antifungal Agents
Aspergillosis
Aspergillus flavus
Biopsy
Diagnosis, Differential
Female
Fibrosis
Humans
Mediastinitis
Mediastinum
Thoracic Surgery, Video-Assisted
Tomography, X-Ray Computed
| | Abstract | Fibrosing mediastinitis due to Aspergillus is rare, particularly in the immunocompetent host. Fibrosing mediastinitis due to Aspergillus species in the immunocompetent patient can be indolent and may be treated with antifungal therapy rather than surgery. We present a 78-year-old nonsmoking, nondiabetic woman with chronic fibrosing mediastinitis due to Aspergillus. Multiple attempts at securing a tissue diagnosis were inconclusive. Ultimately, Aspergillus infection was diagnosed by a video-assisted thoracoscopic surgical biopsy. The patient was started on oral voriconazole, and she remains clinically stable with radiographic improvement. A prolonged, perhaps lifelong, course of antifungal therapy is planned. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 19766844 |
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