| Title | Two new acorane sesquiterpenes from Illicium henryi. | | Author(s) | Song TF, Zhang WD, Xia XH, Shen YH, Liu CM, Lin S, Jin HZ, Li HL | | Institution | Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, China. | | Source | Arch Pharm Res 2009 Sep; 32(9):1233-6. | | Abstract | Two new acorane sesquiterpenes, 10-hydroxyacoronene (1) and 1beta-isopropyl-4beta-methyl-9beta-hydroxy spiro[4.5]dec-6-en-8-one (2), one new natural product, 4-hydroxy-4, 6-dimethyl-1-tetralone (3), and one known acorane sesquiterpene, acoradiepoxide (4) were isolated from the twigs and leaves of Illicium henryi. The structures of the new compounds were elucidated primarily on the basis of analysis of spectroscopic data. In addition, the inhibitory effect on NO production of these compounds were tested. Compounds 1 and 4 exhibited slight inhibitory effects on NO production with IC(50) values of 82.4 microg/mL and 76.5 microg/mL, respectively. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19784579 |
|
