| Title | Changes in prescribing of antiviral medications for influenza associated with new treatment guidelines. | | Author(s) | Hersh AL, Maselli JH, Cabana MD | | Institution | Division of General Pediatrics, University of California, San Francisco, CA, USA. hershad@peds.ucsf.edu | | Source | Am J Public Health 2009 Oct.:S362-4. | | MeSH | Antiviral Agents
Centers for Disease Control and Prevention (U.S.)
Drug Resistance, Viral
Health Care Surveys
Humans
Influenza A Virus, H1N1 Subtype
Influenza, Human
Neuraminidase
Physician's Practice Patterns
United States
| | Abstract | In 2006, the Centers for Disease Control and Prevention recommended discontinuing the use of adamantanes (amantadine and rimantadine) to treat influenza because of high levels of resistance to this class of antivirals. We examined changes in prescribing practices resulting from this recommendation and found that prescribing of adamantanes declined nationwide, with these drugs accounting for approximately 40% of the antivirals prescribed for influenza from 2000 to 2005 and only 2% in 2006. This finding provides evidence of a rapid change in clinical practice associated with the dissemination of treatment guidelines. Evaluating the effectiveness with which public health recommendations are translated into practice is important given the ongoing emergence of resistance to antiviral drugs and a novel H1N1 influenza virus. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, N.I.H., Extramural
| | PubMed ID | 19797750 |
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