Unbound MEDLINE

Tourette's syndrome, trichotillomania, and obsessive-compulsive disorder: How closely are they related? Psychiatry research [Psychiatry Res] Journal article

 
TitleTourette's syndrome, trichotillomania, and obsessive-compulsive disorder: How closely are they related?
Author(s)Ferrão YA, Miguel E, Stein DJ 
InstitutionBrazilian Obsessive-Compulsive Research Consortium, Brazil; Porto Alegre Institute, Universidade Metodista do Sul (IPA), Porto Alegre (RS), Brazil.
SourcePsychiatry Res 2009 Oct 2.
AbstractThe question of whether Tourette's syndrome (TS) and trichotillomania (TTM) are best conceptualized as obsessive-compulsive spectrum disorders was raised by family studies demonstrating a close relationship between TS and obsessive-compulsive disorder (OCD), and by psychopharmacological research indicating that both TTM and OCD respond more robustly to clomipramine than to desipramine. A range of studies have subsequently allowed comparison of the phenomenology, psychobiology, and management of TS and TTM, with that of OCD. Here we briefly review this literature. The data indicate that there is significant psychobiological overlap between TS and OCD, supporting the idea that TS can be conceptualized as an OCD spectrum disorder. TTM and OCD have only partial overlap in their phenomenology and psychobiology, but there are a number of reasons for why it may be useful to classify TTM and other habit disorders as part of the obsessive-compulsive spectrum of disorders.
LanguageENG
Pub Type(s)JOURNAL ARTICLE
PubMed ID19801170
  
Advertise on this site.