| Title | Epidcermolytic hyperkeratosis: a case report. | | Author(s) | Achar A, Naskar B, Laha R, Ray S | | Institution | Department of Dermatology, Mednapore Medical College, Paschim Medinipur 721101. | | Source | J Indian Med Assoc 2009 Mar; 107(3):171-2. | | Abstract | Epidermolytic hyperkeratosis is a rare autosomal dominant genodermatosis that presents at birth as generalised erythema, blisters and erosions. In subsequent periods, erythema and blistering improves but patients go on to develop hyperkeratosis scalingthat is especially prominent along joint flexures, neck, hands and feet. The disease is caused by mutations in either keratin 1 or 10. Treatment options include topical emollients containing glycerin, lactic acid, urea and alpha-hydroxy acid and topical and systemic retinoids. Here a rare case in a 23 years old male is reported with epidermolytic hyperkeratosis and treated successfully with mixture of topical emollients with retinoid and systemic isotretinoin. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19810387 |
|
