| Title | Chronic Surgical Site Infection Due to Suture-Associated Polymicrobial Biofilm. | | Author(s) | Kathju S, Nistico L, Hall-Stoodley L, Post JC, Ehrlich GD, Stoodley P | | Institution | 1 Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital , Pittsburgh, Pennsylvania. | | Source | Surg Infect (Larchmt) 2009 Oct 7. | | Abstract | Abstract
Background: Surgical site infection (SSI) is a common surgical complication; culture-negative SSI presents a particular problem in management.
Methods: Examination of explanted foreign bodies (sutures) using confocal laser scanning microscopy (CLSM) and fluorescent in situ hybridization (FISH) after surgical exploration of a chronic culture-negative SSI.
Results: Confocal microscopy (CM) demonstrated bacilli and cocci attached to the surface of the explanted sutures in a mixed biofilm. Florescent in situ hybridization confirmed that Staphylococci were components of the mixed biofilm. Removal of the foreign bodies (sutures) resolved the chronic infection.
Conclusion: Chronic SSI can arise from underlying bacterial biofilms, which can invest implanted foreign bodies and associated soft tissue surfaces. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19811056 |
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