| Title | Clinical factors predictive of encephalitis caused by Angiostrongylus cantonensis. | | Author(s) | Sawanyawisuth K, Takahashi K, Hoshuyama T, Sawanyawisuth K, Senthong V, Limpawattana P, Intapan PM, Wilson D, Tiamkao S, Jitpimolmard S, Chotmongkol V | | Institution | Department of Medicine, Faculty of Medicine, Srina-garind Hospital, Khon Kaen University, Khon Kaen, Thailand. kittisak@kku.ac.th | | Source | Am J Trop Med Hyg 2009 Oct; 81(4):698-701. | | MeSH | Adolescent
Adult
Aged
Angiostrongylus cantonensis
Animals
Case-Control Studies
Encephalitis
Female
Humans
Logistic Models
Male
Meningitis
Middle Aged
Multivariate Analysis
Odds Ratio
Predictive Value of Tests
Risk Factors
Strongylida Infections
Young Adult
| | Abstract | Angiostrongylus cantonensis is mainly caused eosinophilic meningitis in humans, whereas a minority of patients develop encephalitic angiostrongyliasis (EA). EA is an extremely fatal condition, and the clinical factors predictive of EA have never been reported. A comparison study was conducted in a hospital situated in an endemic area of Thailand. We enrolled 14 and 80 angiostrongyliasis patients who developed encephalitis and meningitis, respectively. Logistic regression analysis was used to assess the clinical variables predictive of encephalitis. Age (adjusted odds ratio [OR], 1.22; 95% confidence interval [CI], 1.05-1.42), duration of headache (adjusted OR, 1.26; 95% CI, 1.03-1.55), and fever > 38.0 degrees C (adjusted OR, 37.05; 95% CI, 1.59-862.35) were identified as statistically significant factors for EA prediction. Elderly patients with angiostrongyliasis experiencing fever and prolonged headaches were at the highest risk of developing EA. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19815890 |
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