Trials review: cardiovascular outcome with intensive glycemic control and implications for patients with type 2 diabetes. Postgraduate medicine [Postgrad Med] Journal article

Title	Trials review: cardiovascular outcome with intensive glycemic control and implications for patients with type 2 diabetes.
Author(s)	Brown SH, Abdelhafiz AH
Institution	Rotherham General Hospital, Rotherham, UK.
Source	Postgrad Med 2009 Sep; 121(5):31-41.
MeSH	Adult Aged Blood Glucose Cardiovascular Diseases Causality Comorbidity Diabetes Complications Diabetes Mellitus, Type 2 Female Follow-Up Studies Great Britain Hemoglobin A, Glycosylated Humans Hypoglycemic Agents Insulin Male Middle Aged Prevalence Tolbutamide Vascular Diseases Young Adult
Abstract	Hyperglycemia is associated with microvascular and macrovascular complications. Intensive glucose control has been shown to reduce microvascular complications. Nevertheless, cardiovascular disease remains the leading cause of death in patients with type 2 diabetes. A positive association exists between hemoglobin A1c level and cardiovascular events, but whether reducing blood glucose will reduce cardiovascular events is still not quite clear. The benefits of intensive glucose control also remain uncertain for the heterogenous group of older patients with type 2 diabetes. This article reviews results of earlier and recently published intervention trials of intensive glucose control and their outcomes and discusses relevant recommendations for adults with type 2 diabetes.
Language	eng
Pub Type(s)	Journal Article Review
PubMed ID	19820272

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