| Title | TWIN PRETERM NEONATES WITH CARDIAC TOXICITY RELATED TO LOPINAVIR/RITONAVIR THERAPY. | | Author(s) | McArthur MA, Kalu SU, Foulks AR, Aly AM, Jain SK, Patel JA | | Institution | From the *Department of Pediatrics, Divisions of daggerPediatric Infectious Disease and Immunology, double daggerNeonatology, and section signPediatric Cardiology, The University of Texas Medical Branch, Galveston, TX. | | Source | Pediatr Infect Dis J 2009 Oct 8. | | Abstract | We report twin neonates who were born prematurely at 32 weeks of gestation to a mother with human immunodeficiency virus infection. One of the twins developed complete heart block and dilated cardiomyopathy related to lopinavir/ritonavir therapy, a boosted protease-inhibitor agent, while the other twin developed mild bradycardia. We recommend caution in the use of lopinavir/ritonavir in the immediate neonatal period. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19820426 |
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