Szilasiová J, Gdovinová Z, Jautová J, Baloghová J, Ficová M, Bohuš P Cutaneous Vasculitis Associated With Interferon beta-1b Treatment for Multiple Sclerosis. [JOURNAL ARTICLE] Clin Neuropharmacol 2009 September/October; 32(5):301-303.
We report a 38-year-old woman with relapsing-remitting multiple sclerosis, treated with subcutaneous injections of interferon beta (IFN-beta)-1b every other day. Disseminated cutaneous lesions were observed after 3 injections. These symptoms reappeared after drug readministration. The histopathological examination of the skin specimens confirmed nonspecific cutaneous lymphocytic vasculitis. The patient's outcome was favorable after corticosteroid placement and discontinuing IFN-beta therapy. Isolated lymphocytic cutaneous vasculitis linked to IFN-beta-1b therapy is suspected as a new association.
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