Thuret I, Chaix ML, Tamalet C, Reliquet V, Firtion G, Tricoire J, Rabaud C, Frange P, Aumaître H, Blanche S
Raltegravir, etravirine and r-darunavir combination in adolescents with multidrug-resistant virus. [Journal Article, Research Support, Non-U.S. Gov't]
AIDS 2009 Nov 13; 23(17):2364-6.
Twelve heavily pretreated, perinatally infected adolescents in virological failure were treated with a combination of raltegravir, r-darunavir and etravirine, as part of an expanded access program in France. After a 12-month median follow-up, viral load was <400 copies/ml in 11 (<50 in six). No grade > 2 side effects were recorded. Additional data and marketing authorizations are awaited, but preliminary results in adolescents with extensive multidrug resistant virus are encouraging.
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