Circulating T-regulatory cells, exercise and the elite adolescent swimmer. Pediatric exercise science [Pediatr Exerc Sci] Journal article | | Title | Circulating T-regulatory cells, exercise and the elite adolescent swimmer. | | Author(s) | Wilson LD, Zaldivar FP, Schwindt CD, Wang-Rodriguez J, Cooper DM | | Institution | Pediatric Exercise Research Center, Department of Pediatrics, University Children's Hospital, University of California, Irvine, CA 92868, USA. | | Source | Pediatr Exerc Sci 2009 Aug; 21(3):305-17. | | Abstract | Brief high intensity exercise induces peripheral leukocytosis possibly leading to a higher incidence of allergic symptoms in athletes undergoing excessive training. We studied the exercise-induced alternation of circulating Tregs and FoxP3+ Tregs due to acute intense swim exercise in elite swimmers (n = 22, 12 males, age = 15.4 yrs). Twelve had prior or current rhinitis or asthma and 10 had no current or prior allergy or asthma. Circulating Tregs increased significantly (p < .001) following exercise (pre = 133 +/- 11.2, post = 196 +/- 17.6) as did FoxP3+ cells (pre = 44, post = 64 cells/microl). Increases in Tregs and FoxP3+ Tregs occurred to the same extent in both groups of adolescent swimmers. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, N.I.H., Extramural
| | PubMed ID | 19827454 |
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