| Title | Predictors of clinical improvement in a randomized effectiveness trial for primary care patients with panic disorder. | | Author(s) | Chavira DA, Stein MB, Golinelli D, Sherbourne CD, Craske MG, Sullivan G, Bystritsky A, Roy-Byrne PP | | Institution | Department of Psychiatry, University of California, San Diego, CA 92037, USA. dchavira@ucsd.edu | | Source | J Nerv Ment Dis 2009 Oct; 197(10):715-21. | | MeSH | Adolescent
Adult
Aged
Anti-Anxiety Agents
Cognitive Therapy
Combined Modality Therapy
Comorbidity
Female
Follow-Up Studies
Humans
Logistic Models
Male
Middle Aged
Panic Disorder
Personality Assessment
Phobic Disorders
Primary Health Care
Probability
Psychiatric Status Rating Scales
Severity of Illness Index
Treatment Outcome
| | Abstract | This study's aim was to prospectively examine and identify a model of demographic, clinical, and attitudinal variables that impact improvement among patients with panic disorder. Subjects were 232 primary care patients meeting criteria for DSM-IV panic disorder. Eligible patients were randomly assigned to a collaborative care intervention or to treatment as usual. Assessments occurred at 3-month intervals during the course of 1 year. In final multivariate logistic regression models, patients with higher anxiety sensitivity and higher neuroticism scores at baseline were less likely to show clinical improvement (using a criterion of 20 or less on the Anxiety Sensitivity Index) at 3 months. Those who were non-white, had higher anxiety sensitivity, and higher overall phobic avoidance at baseline were less likely to show clinical improvement at 12 months. A greater understanding of these predictors may help clinicians identify who is at greatest risk for persistent panic-related symptoms and to plan the intensity of interventions accordingly. | | Language | eng | | Pub Type(s) | Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
| | PubMed ID | 19829198 |
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