Unbound MEDLINE

Visual hallucinations associated with varenicline: a case report. Journal of medical case reports [J Med Case Reports] Journal article

 
TitleVisual hallucinations associated with varenicline: a case report.
Author(s)Raidoo BM, Kutscher EC 
InstitutionDepartment of Psychiatry, Sanford School of Medicine, The University of South Dakota Sioux Falls, SD 57108 USA.
SourceJ Med Case Reports 2009.:7560.
AbstractINTRODUCTION: Varenicline is widely used for smoking cessation. It has shown efficacy over placebo and bupropion in manufacturer-sponsored trials. Those with mental illness were excluded from these trials. There are case reports of exacerbation of mental illness and development of psychiatric symptoms with varenicline use.
CASE PRESENTATION: A 61-year-old male Caucasian being treated for post-traumatic stress disorder, depression not otherwise specified and alcohol dependence, was prescribed varenicline while he was in a post-traumatic stress disorder/alcohol dual diagnosis treatment program. He developed visual hallucinations, which became worse with titration of the medication. These symptoms resolved upon discontinuation of varenicline.
CONCLUSION: Patients with mental illness have a higher incidence of nicotine dependence, and attempts should be made for smoking cessation. Varenicline has not been widely tested in this population. There are reports of exacerbation of mental illness, and probable causation of psychiatric symptoms in the mentally ill. Providers should be aware of this possibility and advise their patients appropriately.
Languageeng
Pub Type(s)Journal Article
PubMed ID19830213
  
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